Who Does Dupuytren's Affect?
Men are affected by Dupuytren's contracture more often than women. Symptoms usually appear later in life, although it has also been observed in people in their 20s.1
Dupuytren's disease is most common among individuals with northern European ancestry. For this reason, Dupuytren's contracture has been called the "Viking disease."2
Dupuytren's runs in families
Dupuytren's contracture can be hereditary. In one study, 68% of people with Dupuytren's contracture were found to have at least one relative who was also affected.3 People with a family history of Dupuytren's tend to develop signs at a younger age than those who do not have family members with the disease. They also tend to have more severe disease involving multiple fingers and both hands.4
References: 1. Luck JV. Dupuytren's contracture: a new concept of the pathogenesis correlated with surgical management. J Bone Joint Surg Am. 1959;41(4):635-664. 2. Hart MG, Hooper G. Clinical associations of Dupuytren's disease. Postgrad Med J. 2005;81(957):425-428. 3. Ling RSM. The genetic factor in Dupuytren's disease. J Bone Joint Surg. 1963;45(4):709-718. 4. Benson LS, Williams CS, Kahle M. Dupuytren's contracture. J Am Acad Orthop Surg. 1998;6(1):24-35.